Piperine

Stand: 10. November 2026 Stomach & Intestine

Piperine is the alkaloid that gives black pepper (Piper nigrum) its characteristic pungency. Beyond the kitchen, piperine is primarily of interest in dietary supplementation, less for its own effects than for its role as an absorption enhancer.

Piperine can increase the bioavailability of certain other substances, meaning it improves how well the body absorbs them. The most well-known combination is with curcumin from turmeric.

Steckbrief

Kind
Alkaloid (pungent substance)
Source
Black pepper (Piper nigrum)
Characteristic property
Improves the absorption of other substances
Common combination
With curcumin (turmeric)
Category
Plant-based secondary substance

Wirkung und Studienlage

The most important property of piperine used in dietary supplementation is its ability to increase the bioavailability of other substances. It can improve absorption in the gastrointestinal tract and influences certain metabolic pathways in the body. For this reason, piperine is specifically added to preparations whose main active ingredient would otherwise be poorly absorbed, most notably curcumin.

Furthermore, piperine itself is being researched for other properties, such as antioxidant effects. However, this research is preliminary. In accordance with European health claim regulations, no health-related claims are permitted for piperine. The focus remains on its function as an absorption enhancer.

Anwendung und Dosierung

In dietary supplements, piperine is usually used in very small amounts, often as a standardized pepper extract. It is typically added to curcumin preparations, where even small amounts of piperine are intended to significantly improve the absorption of the curcumin.

As a standalone preparation, piperine plays almost no role. In practice, you will therefore mostly encounter it as a component of combination products. Adhere to the recommended intake of the respective product.

Sicherheit und Wechselwirkungen

In the small amounts common in dietary supplements, piperine is considered well-tolerated. As a component of pepper, it is an everyday food item.

The very property that makes piperine useful is also the reason for caution: since piperine influences the absorption and degradation of active substances, it can also alter the effect of medications. Those who take medication regularly should therefore clarify the use of piperine-containing preparations with a doctor or at a pharmacy. During pregnancy and breastfeeding, concentrated preparations should only be used after consultation.

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Häufige Fragen

Piperine is the pungent substance in black pepper. In dietary supplementation, it is primarily used to improve the absorption of other substances; the best-known combination is with curcumin.

Curcumin is naturally poorly absorbed by the body. Piperine can significantly improve this absorption, which is why even small amounts are added to many curcumin products.

In the small amounts typical for supplements, piperine is considered well-tolerated. However, because it can influence the effect of medications, people taking medication should consult a doctor regarding piperine-containing preparations.

Fachliche Prüfung

Prof. Dr. med. Dr. phil. Martin Hörning

Arzt, Professor i.R. und Mitbegründer von sanitas

Seit 40 Jahren beschäftigt er sich intensiv mit den Themen Prävention, Gesundheitsförderung, Achtsamkeit, Longevity und Naturheilverfahren. In Herstelle führt er eine kleine Privatpraxis.